When there is no known cause, it is called primary pulmonary hypertension. The lining of the airways become altered, which damages the lung’s cleaning system and allows dust, mucus and bacteria to accumulate and infection to occur.Ī rare disorder in which increased pressure in pulmonary circulation can cause permanent damage to the lungs, a situation that ultimately becomes life-threatening. This genetic disease is characterized by the production of abnormal secretions leading to mucus build-up that impairs lung function.Ī disorder in which the airways become enlarged and distended, forming pockets where infection can develop. This causes the lungs to become stiff and smaller in volume. ILD is a general term that includes a number of chronic lung disorders which cause the walls of the air sac to become inflamed and then scar (pulmonary fibrosis) and may involve the tissue between the air sacs (interstitium).
Pulmonary Fibrosis or Interstitial Lung Disease (ILD).Includes chronic bronchitis and emphysema, involves obstruction of airflow through the airways and out of the lungs and it is usually permanent and progressive. Lung transplantation can prolong and dramatically improve the quality of life for patients with severe end-stage, non-malignant pulmonary disease and no alternative treatment options. A number of diseases and conditions can cause lungs to become so dysfunctional that one or both of them may need to be replaced through transplantation. Conversely, during exhalation the lungs expel waste - carbon dioxide produced when cells use oxygen. When lungs become diseased, they no longer can maintain the necessary exchange of oxygen and carbon dioxide. The lungs play a critical role in the body, extracting oxygen from inhaled air for distribution via the bloodstream to every cell in the body. Living-donor lung transplant require two or more donors, with each donor giving a segment (lobe) of their lung to form an entire lung for the person who is receiving it. A lung transplant is a surgery to replace one or both diseased lungs with healthy lungs from a human donor. The new lung or lungs are usually donated by an organ donor under age 65 who is brain dead but is still on life-support, but may also be donated by living donors.
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